منابع مشابه
The Role of Long Non-Coding RNAs in Ovarian Cancer
Background: Ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. Various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. However, the aim of this review was to investigate the role of long non-co...
متن کاملLong non-coding RNAs in cancer progression
Recent large-scale transcriptome analyses have revealed that transcription is spread throughout the mammalian genomes, yielding large numbers of transcripts, including long non-coding RNAs (lncRNAs) with little or no protein-coding capacity. Dozens of lncRNAs have been identified as biologically significant. In many cases, lncRNAs act as key molecules in the regulation of processes such as chro...
متن کاملthe role of long non-coding rnas in ovarian cancer
background: ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. however, the aim of this review was to investigate the role of long n...
متن کاملLong non-coding RNAs and their significance in human diseases
Protein-coding genes account for only a small fraction of the human genome and most of the genomic sequences are transcriptionally silent, but recent observations indicate significant functional elements, including non-coding protein transcripts in the human genome. Long non-coding RNAs (lncRNAs) have been defined as transcripts of >200 nucleotides without protein-coding capacity that perform t...
متن کاملThe Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, which is associated to the developing prostate cancer in protein coding sequences. The purpose of this r...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2012
ISSN: 1664-8021
DOI: 10.3389/fgene.2012.00219